Zantogin® Gel: A Comprehensive Solution for Menopausal Vulvo-Vaginal Atrophy Harnessing the Power of Zanthalene®
Empowering Women’s Intimate Health with Zantogin® Gel
Women in menopause commonly experience vulvo-vaginal atrophy, a condition characterized by dryness, irritation, and discomfort. Zantogin® Gel is specifically designed to address these challenges, which can significantly impact sexual health and overall quality of life. This innovative product combines carefully selected ingredients that work together to restore vulvar health and comfort. At its core lies Zanthalene®, a groundbreaking ingredient that defines Zantogin® and inspires its name. Derived from natural sources, Zanthalene® offers targeted relief for vulvo-vaginal discomfort
Zanthalene®: The Key to Vulvo-Vaginal Comfort and Relief
Zanthalene® is a natural extract derived from the fruit husks of Zanthoxylum bungeanum (Sichuan pepper), a plant long revered in traditional Chinese medicine. Widely recognized for its analgesic, anti-inflammatory, and soothing properties, Zanthoxylum bungeanum has been traditionally used to treat pain, inflammation, and as a local anesthetic, as validated by a 2017 systematic review by Zhang M et al.
Its efficacy lies in hydroxy sanshools—active compounds that engage in a process called chemesthesis, a sensory phenomenon where nerve endings are desensitized to alleviate discomfort. This mechanism not only reduces itching and burning but also delivers a rapid sensation of relief, mimicking the effects of anesthetics without causing numbness or dependency.
Key studies have demonstrated that hydroxy sanshools act by modulating neuronal activity at the synaptic level. Zanthalene® effectively interrupts the pain and itch signals at their source, offering an immediate soothing effect that makes it uniquely suited for addressing vulvo-vaginal conditions. Unlike conventional treatments that may rely on corticosteroids or systemic drugs, Zanthalene® provides relief through a non-hormonal, targeted approach.
Zantogin® Gel: A Unique Formulation for Comprehensive Care
Zantogin® Gel is much more than a simple moisturizer; it represents a comprehensive solution designed to address multiple symptoms of vulvo-vaginal discomfort. Its patented formulation combines the innovative Zanthalene® with other advanced ingredients, each chosen for its proven efficacy:
- Hyaluronic Acid: Renowned for its exceptional hydrating properties and its ability to support connective tissue repair.
- Xilogel®: A delivery enhancer that ensures the sustained effectiveness of active ingredients. Its standout feature is its ability to reduce the degradation of hyaluronic acid, allowing it to maximize its benefits.
- Centella Phytosome®: Known for promoting healing, enhancing skin resilience, and stimulating fibroblasts to produce collagen.
- Polycarbophil®: Offers long-lasting adhesion to mucosal tissues, prolonging the gel’s effectiveness.
These powerful ingredients work synergistically to deliver remarkable benefits: alleviating symptoms such as dryness, itching, and burning while promoting long-term healing and supporting vulvo-vaginal health.
Clinically Proven Efficacy
Zantogin® Gel’s effectiveness has been validated through rigorous clinical testing. A pivotal study conducted at Sapienza University of Rome demonstrated remarkable improvements in post-menopausal women suffering from Genitourinary Syndrome of Menopause (GSM). Participants reported significant relief from vaginal dryness, itching, and burning after using the gel. (To find out more read our past article here).
An additional study highlighted the efficacy of the cream from the same product line, which also contains Zanthalene® along with other ingredients. In conditions such as vulvar dermatitis and lichen simplex, when used alongside steroid treatments, Zantogin® cream reduced the frequency of steroid application, showcasing its potential as a steroid-sparing alternative.
Why Choose Zantogin® Gel?
- Hormone-Free: Safe for sensitive areas and suitable for women unable to use estrogen-based therapies.
- Scientifically Validated: Backed by clinical studies confirming its effectiveness.
- Innovative Design: A patented formulation combining natural science with advanced delivery systems for optimal results.
Commitment to Quality and Compliance
Zantogin® Gel is a certified medical device, with formal application under European Regulation (EU) 2017/745 (MDR), ensuring its availability and adherence to the highest standards of safety and efficacy. This certification underscores the product’s commitment to providing trusted care for women worldwide.